一、主要科研项目
l 重楼皂苷Ⅱ缓解增塑剂DEHP诱导学习记忆障碍的分子机子研究，2022.01～2022.12，湖南中医药大学中医学一流开放基金（2022ZYX17）
l 雌激素受体β在增塑剂DEHP诱发学习记忆障碍中的作用与机制，2022.01～2024.01，湖南省中药粉体与创新药物研究省部共建国家重点实验室培育基地开放基金（21ptkf1015）
l 重楼皂苷Ⅱ缓解增塑剂DEHP诱导学习记忆障碍的分子机制的研究，2023.01～2025.12，湖南省教育厅青年项目基金（22B0351）
l TNFAIP1与CAMKK1结合在重楼总皂苷抑制增塑剂DEHP诱导的学习记忆障碍中的作用与机制, 2023.01～2025.12,湖南省自然科学基金青年项目（2023JJ40483）
l 基于TNFAIP1介导的泛素化降解途径抑制CAMKIV/CREB通路研究重楼皂苷改善DEHP诱发学习记忆障碍的作用机制研究，2024.01～2026.12，湖南中医药大学重点科研项目
二、发表的主要学术论文（带*号为通讯作者）
[1] Feng Qiu; Yubo Zhou; Yeke Deng; Junzhi Yi; Mengting Gong; Ning Liu; Chenxi Wei; Shuanglin Xiang; Knockdown of TNFAIP1 prevents di-(2-ethylhexyl) phthalate-induced neurotoxicity by activating CREB pathway, Chemosphere, 2020, 241: 125114-125123
[2] Qiu F, He S, Zhang Z, et al. MiR-93 alleviates DEHP plasticizer-induced neurotoxicity by negatively regulating TNFAIP1 and inhibiting ubiquitin-mediated degradation of CK2β. Food Chem. Toxicol. 2023;178:113888
[3] Jin Wang;Feng Qiu; Zilong Zhang; Yu Liu; Qian Zhou; Siyu Dai; Shuanglin Xiang; ChenxiWei ; Clostridium butyricum Alleviates DEHP Plasticizer-Induced Learning and Memory Impairment in Mice via Gut–Brain Axis, Journal of Agricultural and Food Chemistry, 2023, 71(47): 18524- 18537
[4] Ye Xiao; Shulan Huang;Feng Qiu; Xiaofeng Ding; Yi Sun; Chenxi Wei; Xiang Hu; Ke Wei; Shengwen Long; Lina Xie; Yu Xun; Wen Chen; Zhijian Zhang; Ning Liu; Shuanglin Xiang ; Tumor necrosis factorα-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma, EBioMedicine, 2020, 51: 102603-102618
[5] Junzhi Yi; Min Zhu; Feng Qiu; Yubo Zhou; Pan Shu; Ning Liu; Chenxi Wei; Shuanglin Xiang; TNFAIP1 Mediates Formaldehyde-Induced Neurotoxicity by Inhibiting the Akt/CREB Pathway in N2a Cells, Neurotoxicity Research, 2020, 38(1): 184-198
[6] Chenxi Wei; Mouying Chen; Huihui You;Feng Qiu; HuaxiaoWen; Junlin Yuan; Shuanglin Xiang; Xu Yang ; Formaldehyde and co-exposure with benzene induce compensation of bone marrow and hematopoietic stem/progenitor cells in BALB/c mice during post-exposure period, Toxicology and Applied Pharmacology, 2017, 324: 36-44
